Dr. Md. Zahidul Islam Professor, Department of Biotechnology & Genetic Engineering
PROFILE
SHORT BIOGRAPHY
Dr. Md. Zahidul Islam is currently serving as a Professor at the Department of Biotechnology and Genetic Engineering, Jahangirnagar University, Savar, Dhaka, Bangladesh. He joined the Department of Biotechnology and Genetic Engineering at Jahangirnagar University as a Lecturer. Subsequently, he served as an Assistant Professor and Associate Professor in the same Department. Dr. Islam earned his Ph.D. from Shizuoka University, Japan, in 2015. He obtained both his M.S. and B.Sc. degrees in Biotechnology from Khulna University, Bangladesh, in 2003 and 2001, respectively.
He served as a Visiting Associate Professor at the Research Institute of Electronics, Shizuoka University, Japan, from April 1, 2023 to July 30, 2023. As a Postdoctoral Research Fellow, he worked at the Graduate School of Science and Technology, Shizuoka University, during the following periods: October 1, 2015 to December 9, 2016, August 29, 2022 to March 31, 2023 and August 1, 2023 to November 30, 2023.
From 2003 to 2012, Dr. Islam also worked in the Quality Control Departments of several pharmaceutical companies, including Medimet Pharmaceuticals Ltd., General Pharmaceuticals Ltd., Sanofi-Aventis Bangladesh Ltd. (formerly Fisons BD Ltd., Hoechst Marion Roussel Ltd., and Rhone-Poulenc Rorer BD Ltd.), and Incepta Vaccine Ltd.
His current research focuses on revealing the mechanism and mode of action of antimicrobial peptides (such as Magainin 2, Lactoferricin B, LfcinB [4–9], and PGLa) on the bacterial cell membrane using the single-bacterium method. He is also exploring the interaction of cell-penetrating peptides (such as Transportan10 and Poly-arginine) with lipid bilayer membranes using the single-GUV (Giant Unilamellar Vesicle) method. Additionally, he aims to establish a functional and sustainable bio-system engineering process for producing commercial products using various immobilized enzymes.
Dr. Islam has published extensively in national and international peer-reviewed journals across multiple disciplines, including Microbiology, Chemistry, Biochemistry, Physics, Biophysics, Molecular Biology, Biotechnology, and Nanotechnology.
RESEARCH INTEREST
Drug delivery systems, Microbial genetics, Cell-penetrating peptides, Antimicrobial peptides, Single GUV method, Single Bacteria method, Enzyme Technology, Cell biology and Industrial biotechnology
JOURNAL PAPER
29. Md. Zahidul Islam, Farzana Hossain, and Masahito Yamazaki,, Single-cell analysis of antimicrobial compound-induced cell death of bacterial cells., Journal of Antimicrobial Chemotherapy, 2025 Apr 16:dkaf116, 2025. doi: doi: 10.1093/jac/dkaf11628. Sabrina Sharmin, Md. Zahidul Islam, Masahito Yamazaki, Relationship between oligoarginine-induced membrane damage of single Escherichia coli cells and entry of the peptide into the cytoplasm,, Biochemistry and Biophysics Reports, 39, 2024, pp.101777, 2024.
27. Md. Masum Billah, Marzuk Ahmed, Md. Zahidul Islam, Masahito Yamazaki, Processes and mechanisms underlying burst of giant unilamellar vesicles induced by antimicrobial peptides and compounds,, BBA - Biomembranes, 1866, 2024, pp.184330., 2024.
26. Marzuk Ahmed, Md. Zahidul Islam, Md. Masum Billah, and Masahito Yamazaki, Effect of Phosphatidylethanolamine on Pore Formation Induced by the Antimicrobial Peptide PGLa,, Journal of Physical Chemistry B,, 128,, 11, pp.2684–2696., 2024.
25. Sabbir Janee, Shatabdy Saha, Sabrina Sharmin, A.Q. Fuad Hasan, Umme Salma Zohora, Ripa Moni, Md. Zahidul Islam, and Mohammad Shahedur Rahman, Construction and Investigation of Multi-enzyme Immobilized Matrix for the Production of HFCS,, PLOS ONE,, 19, 2, pp.e0292931., 2024.
24. Marzuk Ahmed, Md Zahidul Islam, Md Masum Billah, Masahito Yamazaki, Effect of membrane tension on antimicrobial peptide PGLa-induced pore formation in lipid bilayers,, Biochemical and Biophysical Research Communications, 695, 2024, pp.149452, 2023.
23. Md. Zahidul Islam, Farzana Hossain, Md. Hazrat Ali and Masahito Yamazaki, Relationship between antimicrobial peptides-induced cell membrane damage and bactericidal activity,, Biophysical Journal,, 122,, pp.4645–4655., 2023.
22. Mst. Nusrat Jahan Arbi, Naima Thahsin, Azmery Nurjahan, Sabrina Sharmin, Md. Zahidul Islam, Umme Salma Zohora, Mastura Khatun Ruma, Ripa Moni and Mohammad Shahedur Rahman, Homology Modelling and Docking Studies of Arsenate Reductase of Bacillus megaterium,, Journal of Applied Biotechnology Reports;, 9, 3, pp.707-718., 2022.
21. Ripa Moni, Md. Abdullah Al Noman Khan, Md. Zahidul Islam, Umme Salma Zohora, and Mohammad Shahedur Rahman, Biofilm Fermentation: A Propitious Method for the Production of Protease Enzyme by Bacillus subtilis RB14,, Industrial Biotechnology,, 18, 1, pp.48-59., 2022.
20. Md. Mizanur Rahman Moghal, Madhabi Lata Shuma, Md. Zahidul Islam, and Masahito Yamazaki, A Single GUV Method for Revealing the Action of Cell-Penetrating Peptides in Biomembranes., In: Langel Ü. (eds) Cell Penetrating Peptides. Methods in Molecular Biology, vol 2383. Humana, New York, NY., 2383, 2022.
19. Syed Sajidul Islam, Sayka Alam, Tiluttoma Khan Rajib, Nasrin Akhter, Md. Zahidul Islam, A Generalized Overview of the Possible Pharmacotherapy and Treatments against SARS-CoV-2,, Journal of Contemporary Studies in Epidemiology and Public Health, 2, 1, pp.ep21001, 2021.
18. Md. Zahidul Islam, Mst. Nusrat Jahan Arbi, Ripa Moni, Umme Salma Zohora, Farzana Zafor Nishat, Roksana Khanam and Mohammad Shahedur Rahman, Reduction of Arsenate in a new isolate of Bacillus megaterium,, Jahangirnagar University Journal of Biological Sciences, 8, 2, pp.47-59, 2020.
17. Md. Tanvir Kabir, Md. Shahinur Kabir, Md Kamruzzaman Pramanik, Md. Zahidul Islam and Effat Jahan Tamanna, Production of Chitosan from Oyster Mushroom for -amylase Immobilization, Bangladesh Journal of Botany, 49, 3, pp.593-599, 2020.
16. Md. MizanurRahman Moghal, Md. Zahidul Islam, Farzana Hossain, Samiron Kumar Saha, and MasahitoYamazaki, Role of Membrane Potential on Entry of Cell-Penetrating Peptide Transportan 10 into Single Vesicles,, Biophysical Journal, 118, 57–69, 2020.
15. Shatabdy Saha, Md. Zahidul Islam, Umme Salma Zohora,Mohammed Salahuddin, Sabbir Janee, and Mohammad Shahedur Rahman, Establishment of a Functional and Sustainable Bio-system Engineering Process for the Saccharification of Starch with Industrial Focus,, Jahangirnagar University Journal of Biological Sciences, 8(1): 45–55, 2019.
14. Roksana Khanam, Ripa Moni, Md. Zahidul Islam, Md. Morsaline Billah, Umme Salma Zohora, Farah Sabrin, Mohammad Shahedur Rahman, Study of an Arsenic Metabolizing Bacteria from Arsenic Contaminated Soil of Chandpur District Bangladesh,, Jahangirnagar University Journal of Biological Sciences, 8, 1, pp.57–65, 2019.
13. Farzana Hossain, Md. Mizanur Rahman Moghal, Md. Zahidul Islam, Md. Moniruzzaman, and Masahito Yamazaki, Membrane potential is vital for rapid permeabilization of plasma membranes and lipid bilayers by the antimicrobial peptide lactoferricin B,, The Journal of Biological Chemistry,, 294(27) 10449–10462., 2019.
12. Md. Zahidul Islam, Sabrina Sharmin, Md. Moniruzzaman, and Masahito Yamazaki, Elementary Processes for the Entry of Cell-Penetrating Peptides into Lipid Bilayer Vesicles and Bacterial Cells,, Applied Microbiology and Biotechnology, 102:3879–3892, 2018.
11. Md. Mizanur Rahman Moghal, Md. Zahidul Islam, Sabrina Sharmin, Victor Levadnyy, Md. Moniruzzaman, Masahito Yamazaki, Continuous Detection of Entry of Cell-Penetrating Peptide Transportan 10 into Single Vesicles, Chemistry and Physics of Lipids, 212, 120–129, 2018.
10. Md. Zahidul Islam, Sabrina Sharmin, Victor Levadnyy, Sayed Ul Alam Shibly, and Masahito Yamazaki, Effects of Mechanical Properties of Lipid Bilayers on the Entry of Cell-Penetrating Peptides into Single Vesicles,, Langmuir, 33, 2433−2443, 2017.
09. Md. Moniruzzaman, Md. Zahidul Islam, Sabrina Sharmin, Hideo Dohra, and Masahito Yamazaki, Entry of a Six-Residue Antimicrobial Peptide Derived from Lactoferricin B into Single Vesicles and Escherichia coli Cells without Damaging their Membranes, Biochemistry, 56, 4419−4431, 2017.
08. Toshihiko Oka, Moynul Hasan, Md. Zahidul Islam, Md. Moniruzzaman, and Masahito Yamazaki, Low-pH-Induced Lamellar to Bicontinuous Primitive Cubic Phase Transition in Dioleoylphosphatidylserine/Monoolein Membranes, Langmuir, 33, 12487-12496, 2017.
07. Sabrina Sharmin, Md. Zahidul Islam, Mohammad Abu Sayem Karal, Sayed Ul Alam Shibly, Hideo Dohra and Masahito Yamazaki, Effects of Lipid Composition on the Entry of Cell-Penetrating Peptide Oligoarginine into Single Vesicles,, Biochemistry, 55 (30) 4154–4165, 2016.
06. Sabrina Sharmin, Md. Zahidul Islam, Md. Abdul Jabber, Investigations of medicinal properties of Kalanchoe pinnata under Crassulaceae family,, Bioscience and Bioengineering Communication, 2 (3): 130-136, 2016.
05. Sabrina Sharmin, Md. Zahidul Islam, Md. Abdul Jabber, Isolation and identification of medicinal compounds from Kalanchoe pinnata of Crassulaceae family by 1H NMR., Bioscience and Bioengineering Communication, 2 (2): 123-129, 2016.
04. Md. Zahidul Islam, Jahangir Md. Alam, Yukihiro Tamba, Mohammad Abu Sayem Karal and Masahito Yamazaki, The single GUV method for revealing the functions of antimicrobial, pore-forming toxin, and cell-penetrating peptides or proteins., Phys. Chem. Chem. Phys., 16, 15752-15767, 2014.
03. Md. Zahidul Islam, Hirotaka Ariyama, Jahangir Md. Alam, and Masahito Yamazakia, Entry of cell-penetrating peptide transportan 10 into a single vesicle by translocating across lipid membrane and its induced pores,, Biochemistry, 53, 386-396, 2014.
02. Md. Zahidul Islam, Md. Hasibur Rahman, Fauzia Hafiz, Cultivation of Oyster Mushroom (Pleurotus flabellatus) on different substrates,, International Journal of Sustainable Crop Production, 4(1), 45-48, 2009.
01. Md. Zahidul Islam, Dilara Islam Sharif and Md. Aktar Hossain, A Comparative Study of Azotobacter spp. from Different Soil Samples,, , Journal of Soil Nature, 2(3), 16-19, 2008.
CONFERENCE PAPER
The 2014 International Biophysics Congress”, August 3-7, 2014, Brisbane, Australia.,Md. Zahidul Islam, Hirotaka Ariyama, Md. Jahangir Alam and Masahito Yamazaki, Entry of cell-penetrating peptide transportan 10 into a single vesicle by translocating across lipid membranes and its induce pore. "Brisbane, Australia".
1st International Symposium on Biomedical Engineering, by Ministry of Education, Culture, Sports, Science and Technology (MEXT), November 10-11, 2016, Tokyo Medical and Dental University, Tokyo, Japan.,
Md. Zahidul Islam, Sabrina Sharmin, Victor Levadnyy, Sayed Ul Alam Shibly, and Masahito Yamazaki, Effects of membrane tension on entry of cell-penetrating peptide transportan 10 into single vesicles of lipid membranes, "Tokyo, Japan".
The 61th Annual Meeting of the Biophysical Society, February 11–15, 2017, New Orleans, Louisiana, United States of America (USA).,
Sabrina Sharmin, Md. Zahidul Islam, Masahito Yamazaki and Hideo Dohra, Effects of lipid composition on the entry of cell-penetrating peptide oligoarginine into single vesicles, "Louisiana, United States of America (USA)".
The 2017 international symposium toward the future of advance researches, March 08, 2017, Shizuoka University, Hamamatsu, Shizuoka, Japan.,
Md. Zahidul Islam, Sabrina Sharmin, Victor Levadnyy, Sayed Ul Alam Shibly, and Masahito Yamazaki, The effect of tension on entry of CF-TP10 into single vesicle, "Shizuoka, Japan".
19th International Union for Pure and Applied Biophysics Congress”, July 16-20, 2017, Edinburgh, United Kingdom (UK),
Md. Zahidul Islam, Sabrina Sharmin, Victor Levadnyy, Sayed Ul Alam Shibly, and Masahito Yamazaki, Effects of mechanical property membrane on entry of cell-penetrating peptide into single vesicles, "Edinburgh, United Kingdom (UK)".
19th International Union for Pure and Applied Biophysics Congress”, July 16-20, 2017, Edinburgh, United Kingdom (UK),
Md. Moniruzzaman; Md. Zahidul Islam, Sabrina Sharmin, Hideo Dohra, and Masahito Yamazaki, Entry of Lactoferricin B (4-9) into single vesicles and E. coli without damaging their membrane, "Edinburgh, United Kingdom (UK)".
64th Annual Meeting of the Biophysical Society, February 15-19, 2020, San Diego, California, United States of America (USA),
Farzana Hossain, Md. Mizanur Rahman Moghal, Md. Zahidul Islam, Md. Moniruzzaman, Masahito Yamazaki, Membrane potential is vital for rapid permeabilization of plasma membranes and lipid bilayers by the antimicrobial peptide lactoferricin B, "California, United States of America (USA)".
Proceedings of the 15th Takayanagi Kenjiro Memorial Symposium (November 12-13, 2013, Hamamatsu, Japan), S7-4-1~5.,
J. Md. Alam, Md. Zahidul Islam, T. Tsuboi, Md. A. S. Karal, and M. Yamazaki, The Single GUV Method for Probing Elementary Processes of Peptide/Proteins-Induced Pore Formation in Biomembranes.
Proceedings of the 16th Takayanagi Kenjiro Memorial Symposium (November 11-12, 2014, Hamamatsu, Japan), PS1-3-1~5.,Md. Zahidul Islam, HirotakaAriyama, Jahangir Md. Alam, and Masahito Yamazaki, “Visualization of entry of cell-penetrating peptide transportan 10 into a single vesicle by translocating across lipid membranes and its induced pores”,
Proceedings of the 17th Takayanagi Kenjiro Memorial Symposium (November 17-18, 2015, Hamamatsu, Japan), 29~33.,Md. Zahidul Islam, Sabrina Sharmin, and Masahito Yamazaki, “Effect of cholesterol on the entry of cell-penetrating peptide Transportan 10 (TP10) into a single vesicles”,
Proceedings of the 18th Takayanagi Kenjiro Memorial Symposium (November 15-16, 2016, Hamamatsu, Japan).,Sabrina Sharmin, Md. Zahidul Islam, Mohammad Abu Sayem Karal, Shibly Sayed Ul Alam, Hideo Dohra and Masahito Yamazaki, “Effects of mechanical property of lipid membranes on the entry of cell-penetrating peptide oligoarginine into a single vesicle”,.
Proceedings of the 19th Takayanagi Kenjiro Memorial Symposium (November 21-22, 2017, Hamamatsu, Japan).,Md. Moniruzzaman; Md. Zahidul Islam, Sabrina Sharmin, Hideo Dohra and Masahito Yamazaki, “Entry of Antimicrobial Peptide Lactoferricin B (4-9) into single vesicles and E. coli cells”,
Proceedings of the 20th Takayanagi Kenjiro Memorial Symposium (November 27-29, 2018, Hamamatsu, Japan).,Md. Mizanur Rahman Moghal, Md. Zahidul Islam, Sabrina Sharmin, and Masahito Yamazaki, Continuous Detection of Entry of Cell-Penetrating Peptide Transportan 10 into Single Vesicles,”
BOOK CHAPTER
Md. Mizanur Rahman Moghal, Madhabi Lata Shuma, Md. Zahidul Islam, and Masahito Yamazaki, A Single GUV Method for Revealing the Action of Cell-Penetrating Peptides in Biomembranes., Methods in Molecular Biology, vol 2383. Humana, New York, NY., 2022. doi: doi.org/10.1007/978-1-0716-1752-6_11Teaching
| Course Code | Course Title | Semester/Year |
|---|---|---|
| BGE 501 | Advanced Agricultural Biotechnology | Master of Science |
| BGE 503 | Enzyme Technology | Master of Science |
| BGE 512 | Enzyme Technology Practical | Master of Science |
| BGE 402 | Medical and Pharmaceutical Biotechnology | Bachelor of Science: 4th Year |
| BGE 301 | Microbial Genetics | Bachelor of Science: 3rd Year |
| BGE 213 | Metabolism Practical | Bachelor of Science: 2nd Year |
| BGE 202 | Biophysical Chemistry | Bachelor of Science: 2nd Year |
| BGE 105 | Basic Biochemistry | Bachelor of Science: 1st Year |
Academic Info
Period: 2015
Doctor of Science
Period: 2003
Master of Science in Biotechnology and Genetic Engineering
Period: 2000
Bachelor of Science in Biotechnology and Genetic Engineering
Period: 1995
Higher Secondary Certificate (Science)
Period: 1993
Secondary School Certificate (Science)
Experience
Position: Professor
Period: 03.01.2025 to till now
Teaching: Delivering lectures and lessons, preparing course materials, and evaluating students’ performance through exams, assignments, and other assessments. Research: Conducting original research, publishing academic articles and books, and presenting their findings at conferences. Mentoring: Advising students and serving as role models to assist in directing their professional and academic development. Service: Participating in departmental and institutional activities, serving on committees, and mentor new faculty members. Professional Development: Expanding professional development, going to conferences and workshops, and collaborating with peers to advance their research and teaching objectives.
Position: Visiting Associate Professor
Period: 01.04.2023 to 30.07.2023
To reveal the mechanism and mode of action of antimicrobial peptides (Magainin 2, Lactoferricin B, LfcinB [4-9] and PGLa) on cell membrane by single Bacteria method.
Position: Associate Professor
Period: 30.01.2020 to 02.01.2025
Teaching: Delivering lectures and lessons, preparing course materials, and evaluating students’ performance through exams, assignments, and other assessments. Research: Conducting original research, publishing academic articles and books, and presenting their findings at conferences. Mentoring: Advising students and serving as role models to assist in directing their professional and academic development. Professional Development: Expanding professional development, going to conferences and workshops, and collaborating with peers to advance their research and teaching objectives.
Position: Assistant Professor
Period: 24.12.2018 to 29.01.2020
Teaching: Delivering lectures and lessons, preparing course materials, and evaluating students’ performance through exams, assignments, and other assessments. Research: Conducting original research, publishing academic articles and books, and presenting their findings at conferences. Mentoring: Advising students and serving as role models to assist in directing their professional and academic development.
Position: Lecturer
Period: 12.12.2016 to 23.12.2018
Teaching: Delivering lectures and lessons, preparing course materials, and evaluating students’ performance through exams, assignments, and other assessments. Research: Conducting original research, publishing academic articles and books, and presenting their findings at conferences. Mentoring: Advising students and serving as role models to assist in directing their professional and academic development.
Position: Postdoctoral Research Fellow
Period: 01.10.2015 to 09.12.2016, 29.08.2022 to 31.03.2023 and 01.08.2023 to 30.11.2023
To reveal the mechanism and mode of action of antimicrobial peptides (Magainin 2, Lactoferricin B, LfcinB [4-9] and PGLa) on cell membrane by single Bacteria method and cell penetrating peptides (Transportan10 and Poly-arginine) on cell membrane by single GUV method.
Position: Research Fellow
Period: 01.10.2012 to 30.09.2015
To reveal the mechanism and mode of action of antimicrobial peptides (Magainin 2, Lactoferricin B, LfcinB [4-9]) and cell penetrating peptides (Transportan10 and Poly-arginine) on cell membrane by single GUV method.
Position: Executive officer, Quality Control (Chemical and Microbiology Lab)
Period: 17.05.2010 - 24.09.2012
Preparation of all kinds of document regarding Quality Control and Quality Assurance Department. Biochemical, serological, microbiological and animal level testing of all kinds of vaccine. Review, preparation and update of SOPs, specifications and standard methods. To maintain safety in the laboratory and implement environment, health and safety instructions.
Position: Head of Microbiology Department
Period: 15.09.2005 - 16.05.2010
Supervised and Approved of routine microbiological analysis of raw materials, products (Antibiotic and Non-Antibiotic), and follow-up environmental monitoring, ensure aseptic processing and all microbiological release activities. To run microbiology laboratory effectively and efficiently, maintain GLP. Laboratory and follow up of their implementation. Ensure aseptic manufacturing and timely microbiological support.
Position: Quality Control Officer (Microbiologist)
Period: 04.08.2004 - 14.09.2005
Microbiological evaluation of raw materials & finished product including routine microbiological evaluation of purified water, total viable count of syrup, suspension and cream also carry out chemical and physical analysis of raw, semi-finished and finished product, new analytical method development preparation of dossier, and also look after the affairs of QC Department.
Position: Quality Control Officer (Microbiologist)
Period: 02.08.2003 - 03.08.2004
Microbiological assay of antibiotics, sterility test of injectable products, water for injection, routine environment monitoring system of Grade-A, Grade-B, Grade-C production area, microbial limit test of suspension and syrup, routine maintenance of microorganism and instrument of microbiology section. Test and analysis of incoming raw materials, intermediate and finished products.
Contact
Dr. Md. Zahidul Islam
Professor
Department of Biotechnology & Genetic Engineering
Jahangirnagar University, Savar, Dhaka-1342, Bangladesh.
Cell Phone: +88-01787-086965; +88-01716-079115
Work Phone: 02224491045-51; Ext.- 2406 (Off.)
Email: zahidul@juniv.edu
, zahidul_ku@yahoo.com; zahidul.islam@bgeju.edu.bd
