Shahdat Hossain
Shahdat Hossain Professor, Department of Biochemistry & Molecular Biology

PROFILE


SHORT BIOGRAPHY

Dr. Shahdat Hossain was born on 1 January 1967 in a village  of Tangail District. He secured 9th position in Secondary School Certificate Examination (Agriculture Branch) of Dhaka Board in 1981. After completing his college education in Dahanbary Collge in 1983 from the same board he took admission in the University of Dhaka, Bangladesh, from where he earned his B.Sc. and M.Sc. degrees in Biochemistry. He then went to Shimane Medical University, Japan and earned his Ph.D. in 1999 from the Department of Physiology-I. His research work was on the effect of fish oil components, particularly docosahexaenoic acid (C22:6, omega-3) and eicosapentaenoic acid (EPA, C20:5, omega-3) on hypercholesterolemia, hypertension, platelet aggregation, membrane physicochemical properties, brain oxidative stress, neurodegenerative diseases, such as Alzheimer’s disease (AD). Back in Bangladesh he joined the Jahangirnagar University as a lecturer as one of three founder members of the Dept. of Biochemistry and Molecular Biology in 2001. His tremendous hard work helped the newly formed department to make it as one of the most potential departments of the University, which is now running with 28 faculties and >9 staffs and high standard laboratories. He was promoted to the post of the professor in 2010. He also served as the chairman of the department.

Dr. Hossain sees the Biochemistry and Molecular Biology as a living novel, where a story starts and ends with numerous thrill. Our talking, listening, seeing, singing, staring, stimulation, response, our sorrowfulness, our happiness, our decision to commit suicide, a prey’s fight or flight from its predator, the wobbling of a caterpillar, a butterfly’s erratic flight around flowers or even the closeness of a tiny bacterium towards a nutrient molecule—all these physiological processes and behaviors underlie Biochemistry and Molecular Biology. Molecules crosstalk by bonding/nonbonding interactions. The cell, which consists of billions of molecules, communicates by signals. Cells’ communications are manifested at different tissues/ organ levels, which ultimately constitute the organisms, like us and our behaviors and the way of thinking for which we go ahead. These are of a great mystery, where hundreds of thousands of molecular episodes are happening.  As a teacher, he always thinks about the great philosophy of these molecular machineries that lead to the (molecular)movies at the cellular levels and comprises our body and keep us alive. He says we are nothing but the composite behaviors of these molecules and/or cells. Currently, he is leading different projects. Some of them are aimed at amelioration of Alzheimer’s disease and Parkinson’s disease in model rats and neurotoxic effect(s) of heavy metals on brain proteins. As a recognition, Professor Hossain was honored as a recipient of the Gold Medal award of the Bangladesh Academy of Science (BAS) and Third World Academy of Science (TWAS) award.

RESEARCH INTEREST

Neurodegenerative diseases such as Alzheimer’s Disease, Parkinson’s Disease, Lipid Nutrition,Neurochemistry etc

Journal Paper

     

1.     Shahdat Hossain, Jakir Hussain, Sujan Bhowmick, Marzan Sakar, Mafroz Basunia, Abdullah Al Mamun, Yoko Tanabe, Michio Hashimoto, Osamu Shido,  Lead exposure decreases the level of docosahexaenoic acid (DHA, C22:6, w-3) in the milk and mammary gland tissues of lactating mother rats. Drugs and Chemical Toxicolgy, 2018 (In press).

2.     Shahdat Hossain, Masud Hossaina, Sujan Bhowmick, Jakir Hussain, Marzan Sarkar, Md. Mahmudul Hasan, Mafroz Ahmed Basunia, Mahmudul Hasan. Oral administration of Ganoderma lucidum extract protects gingival tissues against proinflammatory TNF and oxidative stress in periodontitis model rats. Journal Chinese Traditional Medicine, (2018), In press.

3.     Michio Hashimoto, Shahdat Hossain, Masanori Katakura, Abdullah Al Mamun, Osamu. Docosahexaenoic Acid Helps to Lessen Extinction Memory in Rats. Molecules, 2018, 23, 451; doi:10.3390/molecules23020451

4.     Masud Hossain, Sujan Bhowmick, Marzan Sarkar, Mafroz Ahmed Basunia, Bazlul Karim Choudhury, Shahdat Hossain. Effects of Ganoderma Lucidum on Palliative Care In Oral Squamous Cell Carcinoma (OSCC) Patients: An Evidence of Excellent Postoperative Support for Cancer Patients. IOSR Journal of Dental and Medical Sciences 17: 76-87, 2018.

5.     Shahdat Hossain, Jahirul Islam, Sujan Bhowmick, Mozammel Haque, Asiqur Rahaman. Effects of Syzygium cumini seed extract on the memory loss of Alzheimer’s disease model rats. Advances in Alzheimer’s disease, 6, 53-73, 2017.

6.     Marzan Sarkar, Sujan Bhowmick, Jakir Hussain, Mahmudul Hasan, Shahdat Hossain Hot Water Extract of Moringa oleifera Leaves Protects Erythrocytes from Hemolysis and Major Organs from Oxidative Stress in vitro. Journal of Basic And Applied Research, 3(3): 120-126, 2017.

7.     Shahdat Hossain, Rashed Ahmed, Sujan Bhowmick, Abdullah Al Mamun, Michio Hashimoto, Proximate composition and fatty acid analysis of Lablab purpureus (L.) legume seed: implicates to both protein and essential fatty acid supplementation, SpringerPlus (2016) 5: 1899. doi:10.1186/s40064-016-3587-1.

8.     S Hossain, S Bhowmick, S Jahan, L Rozario, M Sarkar, S Islam, ... .Maternal lead exposure decreases the levels of brain development and cognition-related proteins with concomitant upsurges of oxidative stress, inflammatory response and apoptosis in the offspring rats, NeuroToxicology, 56, 150-158, 2016.

9.     M Hashimoto, S Hossain, AA Mamun, K Matsuzaki, H Arai. Docosahexaenoic acid: one molecule diverse functions, Critical Reviews in Biotechnology, 2016. DOI: 10.1080/07388551.2016.1207153

10.  S Hossain, M , Hashimoto, M Katakura, M Abdullah Al, O Shido. Medicinal value of asiaticoside for Alzheimer’s disease as assessed using single-molecule-detection fluorescence correlation spectroscopy, laser-scanning microscopy, transmission electron microscopy, and in silico docking. BMC Complementary and Alternative Medicine, 15 (118), 2016.

11.  M Hashimoto, T Inoue, M Katakura, S Hossain, Al Mamun, K Matsuzaki. Differential effects of docoosahexaenoic and arachidonic acid on fatty acid composition and myosin heavy chain-related genes of slow-and fast-twitch skeletal muscle tissues. Molecular & Cellular Biochemistry, 415 (1-2), 169-181, 2016.

12.  S Hossain, S Bhowmick, Sarkar M, Hassan M, et al.,  Rice Germosprout Extract Protects Erythrocytes from Hemolysis and the Aorta, Brain, Heart, and Liver Tissues from Oxidative Stress In Vitro. Evidence-Based Complementary and Alternative Medicine, Volume 2016, Article ID 9587020, 9 pages, http://dx.doi.org/10.1155/2016/9587020

13.  M Hashimoto, S Kato, Y Tanabe, M Katakura, AA Mamun, M Ohno, Hossain S, Onoda K, Yamaguchi S, Shido O. Beneficial effects of dietary docosahexaenoic acid intervention on cognitive function and mental health of the oldest elderly in Japanese care facilities and nursing homes. Geriatrics & Gerontology International, 2016, Jan 28. doi: 10.1111/ggi.12691.

14.  Ishtiaq Mahmud, Dip Bhowmik, Shahdat Hossain, Interrelationship of Serum Uric Acid Levels and Cardiovascular Disease Risk Factors in Bangladeshi Patients Treated with Antihypertensive Drugs, British Journal of Medicine and Medical Research, ISSN: 2231-0614,17(5): 2016, DOI: 10.9734/BJMMR/2016/27559

15.  M Hashimoto, S Hossain, K Matsuzaki, A Al Mamun, H Arai, O Shido Computational Analyses of Docosahexaenoic Acid (DHA, C22: 6, n-3) with Alzheimer’s Disease-Causing Amyloid Peptide Aβ1-42 Reassures Its Therapeutic Utility, Advances in Alzheimer's Disease, 5 (02), 73, 2016.

16.  AA Mamun, M Hashimoto, S Hossain, M Katakura, H Arai, O Shido, Confirmation of the Experimentally-Proven Therapeutic Utility of Madecassoside in an Aβ1-42 Infusion Rat Model of Alzheimer’s Disease by in Silico Analyses, Advances in Alzheimer’s Disease, 4, 37-44, 2015.

17.  FR Mowsumi, A Rahaman, NC Sarker, BK Choudhury, S Hossain, In vitro relative free radical scavenging effects of Calcybe indica (milky yster) and pleurotus djamr  (pink oyster). World Journal of Pharmacy and Pharmaceutical Sciences. 4(07):186-195, 2015.

18.  M Rahman, S Hossain, Computational Prediction of Anti-breast Cancer Effect of Abruquinones from Abrus Precatorius L.  Biorsearch Communications, 1 (01), 2015.

19.  Michio Hashimoto, Masanori Katakura, Yoko Tanabe, Abdullah Al Mamun, Takayuki Inoue, Shahdat Hossain, Makoto Arita, Osamu Shido. N-3 fatty acids effectively improve the reference memory-related learning ability associated with increased brain docosahexaenoic acid-derived docosanoids in aged rats. Biochimica et Biophysica Acta:Molecular and Cell Biology of Lipids,1851: 203–209, 2015.

20.  Fowzia Akter, Mozammel Haque, Jahirul Islam, Asiqur Rahaman, Sujan Bhowmick, Shahdat Hossain. Chronic administration of Curcuma longa extract improves spatial memory-related learning ability in aged rats by inhibiting brain corticohippocampal oxidative stress and TNFa . Advances in Alzheimer’s disease, 4:78-89. 2015.

21.  Shahdat Hossain, Sujan Bhowmick, Saiful Islam, Liza Rozario, Sabrin Jahan, Mehedi Hassan, Marzan Sarkar, Bazlul Karim Choudhury, Sohel Ahmed and Hussain Shahjalal. Oral administration of Ganoderma lucidum to lead-exposed rats protects erythrocytes against hemolysis: implicates to anti-anemia.  Evidence-Based Complementary and Alternative Medicine Volume 2015 (2015), Article ID 463703, 8 pages, http://dx.doi.org/10.1155/2015/463703

22.  AA Mamun, M Hashimoto, M Katakura, S. Hossain, O Shido. Neuroprotective effect of thymoquinone against glutamate-induced toxicity in SH-SY5Y cells. Current Topics in Nutraceutical Research, 13: 143-152, 2015.

23.  M Rahman, R Asiqur, S Nirod Chandra, C Bazlul Karim, H Shahdat. In vitro relative free radical scavenging effects of Calocybe indica (Milky Oyster) and Pleurotus djamor (pink Oyster). World Journal of Pharmacy and Pharmaceutical Sciences, 4(07):186-195, 2015.

24.  AA Mamun, M Hashimoto, S Hossain, M Katakura, H Arai, O Shido. Confirmation of the Experimentally-Proven Therapeutic Utility of Madecassoside in an Aβ1-42 Infusion Rat Model of Alzheimer’s Disease by in Silico Analyses. Advances in Alzheimer ’s disease, 4: 37-44. 2015.

25.  Michio Hashimoto, Shahdat Hossain, Masanori Katakura, Abdullah Al Mamun, Osamu Shido. The Binding of Aβ1–42 to Lipid Rafts of RBC is Enhanced by Dietary Docosahexaenoic Acid in Rats: Implicates to Alzheimer’s Disease. Biochim Biophys Acta, 1848(6):1402-1409, 2015.

26.  Abdullah Al Mamun, Michio Hashimoto, Mosanori Katakura, Kentaro Matsuzaki, Shahdat Hossain, Hiroyuki Arai, Osamu Shido. Neuroprotective Effect of Madecassoside Evaluated Using Amyloid 1-42-Mediated in Vitro and in Vivo alzheimer’s Disease Models. International Journal of Indigenous Medicinal Plants 47(2):1669-1682, 2014.

27.  Mozammel Haque, Jahirul Islam, Asiqur Rahaman, Fowzia Akter Selina, Mohammad Azizur Rahman, Mahmudul Hasan, Shahdat Hossain. Raphanus sativus ameliorates atherogeneic lipid profiles in hypercholesterolemic rats and hypercholesterolemia-associated peroxidative liver damage. Journal of Advances in Chemistry, 7(3):1385-1394, 2014.

28.  Jahirul Islam, Mozammel Haque, Asiqur Rahaman, Shahdat Hossain. Syzygium cumini (L.) Seed Extract Protects Embryofoetal Brains against Intrauterine Oxidative Toxicity in Rats during Hypoxia-reperfusion Injury. International Journal for Pharmaceutical Research Scholars, 3(I-3):170-177, 2014.

29.  Alak Kanti Dutta, Muhammad Ali Siddiquee, Shahdat Hossain, Yearul Kabir. Finlay Green Tea possesses the Highest in vitro Antioxidant Activity among the Twenty Commercially Available Tea Brands of Bangladesh. Malaysian Journal of Pharmaceutical Sciences, 11(2): 11-20, 2013.

30.  Nusrat Fatima, Fowzia Akter Selina, Mozammel Haque, Jahirul Islam, Mijanur Rahman, Asiqur Rahaman, Shahdat Hossain. A Polyherbal Extract Formulation Lowers the Cardiovascular Disease Risk Factors Concurrently with Systemic Oxidative Status in Normocholesterolemic Rats. The Global Journal of Pharmacology, 7 (4): 436-441, 2013.

31.  Zinat Mahal, Tanzir Ahmed, Md Shahdat Hossain, Abdullah Al Mahin, Harun Or Rashid, Tabassum Mumtaz.Use of Pleurotus sajor-caju in upgrading green jute plants and jute sticks as ruminant feed. Journal of BioScience and Biotechnology, 2(2): 101-107, 2013.

32.  Shahdat Hossain, Mijanur Rahman, Nusrat Fatima, Mozammel Haque, Jahirul Islam. Leucas zeylanica (L.) R. Br. Protects ethanol and hydrogen peroxide- induced oxidative stress on hepatic tissue of rats. International Current Pharmaceutical Journal, 2(8):148-151, 2013.

33.  Mijanur Rahman, Mafroz Ahmed, Taslima Nahar, Borhan Uddin, Nusrat Fatima, Ferdousi Rahman, Fowzia Akter, Asiqur Rahaman, Mozammel Haque, Jahirul Islam, Shahdat Hossain. Innovare. Spectra of alternative therapies of hypercholesterolemia by dietary bioactives: emphasis on nutrigenomics of polyphenols. Innovare Journal of Food science, 1: 1-7, 2013.

34.  Asiqur Rahaman, Shahdat Hossain, Mijanur Rahman, Ibrahim Hossain, Taslima Nahar, Borhan Uddin, Ibrahim Khalil. Syzygium Cumini (L.) Seed Extract Improves Memory Related Learning Ability of Old Rats in Eight Arm Radial Maze. Journal of Pharmacognosy and Phytochemistry, 1: 85-94, 2013.

35.  M Rahman, A Rahman, MA Basunia, N Fatima, S Hossain. Antihemolytic Activity of Clerodendrum viscosum Vent. Is Mediated by its Antioxidant Effect. European Journal of Medicinal Plants, 3(1): 127-134, 2013.

36.  F. R. Mowsumi, M. M. Rahman, A. Rahaman, S. Hossain. Ganoderma lucidum prevents paracetamol-induced acute hepatotoxicity in rats. Journal of Scientific Research, 5 (3): 573-578, 2013.

37.  Rahman MM, Rahaman A, Nahar T, Uddin B, Basunia MA, Hossain S.  Antioxidant and antimicrobial activity of Pleurotus florida caultivated in Bangladesh. J. of  Medicinal Plants Studies 1(3):166-175, 2013.

38.  Rahman M, Hossain S. Centella asiatica (linn.) urban extract ameliorates oxidative stress on erythrocyte membrane. Innovare Journal of Ayurvedic Science, 1: 1-4. 2013.

39.  Mijanur Rahman, Shahdat Hossain, Asiqur Rahaman, Nusrat Fatima, Taslima Nahar, Borhan Uddin and Mafroz Ahmed Basunia. Antioxidant activity of Centella asiatica: Effect of extraction solvent Polarity. Journal of Pharmagcognosy and Phytochemistry, 1(6): 27-32, 2013.

40.  Taslima Nahar, Borhan Uddin, Shahdat Hossain, Abdul Mannan Sikder, Sohel Ahmed. Aloe vera gel protects liver from oxidative stress-induced damage in experimental rat model. Journal of Complementary and Integrative Medicine, 10(1):1-7, 2013.

41.  K Miwa, M Hashimoto, S Hossain, M Katakura, O Shido. Evaluation of the inhibitory effect of docosahexaenoic acid and arachidonic acid on the initial stage of amyloid β1-42 polymerization using fluorescence correlation spectroscopy. Advances in Alzheimer’s disease, 2(2): 66-72, 2013.

42.  Michio Hashimoto,Takayuki Inoue, Masanori Katakura, Yoko Tanabe,Shahdat Hossain, Satoru Tsuchikura, Osamu Shido.  Prescription n-3 fatty acids, but not eicosapentaenoic acid alone, improve reference memory-related learning ability by increasing brain-derived neurotrophic factor levels in SHR.Cg-Leprcp/NDmcr rats. Neurochemical Research, 38(10): 2124-2135, 2013.

43.  Masanori Katakura, Michio Hashimoto, Toshiyuki Okui, Hossain Md Shahdat,. KentaroMatsuzaki, and Osamu Shido Omega-3 Polyunsaturated Fatty Acids Enhance Neuronal. Differentiation in Cultured Rat Neural Stem Cells. Stem Cells International, Volume 2013, Article ID 490476, 9 pages http://dx.doi.org/10.1155/2013/490476

44.  S. Hossain, L. Ali, M. Rahman and M.I. Khalil. Leptin Levels of Bangladeshi Type 2 Diabetic and Nondiabetic Subjects: Effect of Anthropometric, Biochemical and Macro-nutritional Parameters. World Applied Sciences Journal, 28 (10): 1341-1347, 2013.

45.  MMT Islam, A Talukder, T Rahman, JMM Islam, S Hossain, HU Shekhar. Food Functionality of Popular and Commonly Consumed Indigenous Vegetables and Fruits from Bangladesh. Food and Nnutrition Sciences, 4:741-747, 2013.

46.  Md. Bazlul Karim Choudhury, A. J. Kakon, Ferdousi Rahman Mowsumi, Taufiqur Rahman, Mahbuba Moonmoon, Md. Masud Hossain, Bimal Chandra Dey4 and Md. Shahdat Hossain. Effect of Oyster mushroom (Pleurotus ostreatus) on Renal Function of Hypertensive Male Volunteers. Bangladesh Journal of Mushroom, 7(1): 9-16. 2013.

47.  Md. Bazlul Karim Choudhury1, A. J. Kakon, Bimal Chandra Dey2, Selima Akhter3, Ferdousi Rahman Mowsumi, Md. Shahdat Hossain4 and M. Shahabuddin Kabir Choudhuri. Influence of Oyster Mushroom (Pleurotus ostreatus) on Lipid Profile of Bangladeshi Male Volunteers during Ramadan Fast. Bangladesh Journal of Mushroom, 6(1): 63-71, 2012.

48.  Md. Bazlul Karim Choudhury, Mohammed Anwarul Kabir Choudhury, Nirod Chandra Sarker, Taufiqur Rahman, A. J. Kakon, Ferdousi Rahman Mowsumi, Md. Akhtaruzzaman3 and Md. Shahdat Hossain. Influence of Oyster Mushroom (Pleurotus ostreatus) to Improve Hemoglobin Level of Anemic Female Volunteers Suffering from Type 2 Diabetes Mellitus. Bangladesh Journal of Mushroom, 6(2): 1-8, 2012.

49.  Md. Bazlul Karim Choudhury, Taufiqur Rahman, Mst. Masuda Begum, Afsana Ahmed, Md. Shahdat Hossain and M. Shahabuddin Kabir Choudhuri. One month Ramadan Fast Improves Lipid Profile Status of Bangladeshi Male Volunteers. Journal of  Dhaka National Medical College Hospital, 18 (02): 37-42, 2012.

50.  Shahdat Hossain, Asiqur Rahaman, Taslima Nahar, Mafroz, Ahmed Basunia, Ferdousi Rahman, Borhan Uddin, Masum Shahriar, Ishtiaq Mahmud. Syzygium cumini (L.) skeels seed extract ameliorates in vitro and in vivo oxidative potentials of the brain cerebral cortex of alcohol-treated rats. Oriental Pharmacy and Experimental Medicine, 12(1):59-66, 2011.

51.  Michio Hashimoto, Ryuichi Tozawa, Masanori Katakura, Hossain Shahdat, Abdul Md Haque, Yoko Tanabe, Shuji Gamoh, Osamu Shido. Protective effects of prescription n-3 fatty acids against impairment of spatial cognitive learning ability in amyloid β-infused rats.  Food & function, 2(7):386-94, 2011.

52.  Shahdat Hossain, Imrul Hasan Chowdhury, Mafroz Ahmed Basunia et al. Syzygium cumini Seed Extract Protects the Liver Against Lipid Peroxidation with Concurrent Amelioration of Hepatic Enzymes and Lipid Profile of Alcoholic Rats. Journal of Complementary and Integrative Medicine, 1(8): 1-17, 2011.

53.  Ishtiaq Mahmud, Zillur Rahman, Shamima Islam Keka, Sudip Devnath, Nuruzzam Masum, Shahdat Hossain.  Hyperphosphataemia is associated with the diabetes-related cardiovascular risk factors. Journal of Oleo Science, 60(2):79-85, 2011.

54.  Michio Hashimoto, Masanori Katakura, Shahdat Hossain, Koji Miwa, Azizur Rahman, Toshio Shimada, Osamu Shido. Docosahexaenoic acid withstands the Aβ (25-35)-induced neurotoxicity in SH-SY5Y cells. Journal of Nutritional Biochemistry, 22:22-9, 2011.

55.  Michio Hashimoto, Masanori Katakura, Toru Nabika, Yoko Tanabe, Shahdat Hossain, Satoru Tsuchikura, Osamu Shido. Effects of Hydrogen-Rich Water on Abnormalities in SHR.Cg-Leprcp/NDmcr Rat- a Metabolic Syndrome Model Rat. Medical Gas Research, 1:26  doi:10.1186/2045-9912-1-26, 2011.

56.  Borhan Uddin, Taslima Nahar, Mafroz Ahmed Basunia and Shahdat Hossain. Paederia foetida protects liver against hepatotoxin-induced oxidative damage. Advances in Biological Research, 5(5-5):267-272, 2011.

57.  Michio Hashimoto, Shahdat Hossain. Neuroprotective and ameliorative actions of polyunsaturated fatty acids against neuronal diseases: beneficial effect of docosahexaenoic acid on cognitive decline in Alzheimer's disease. Journal of Pharmacological Sciences, 116(2):150-62, 2011.

58.  Md. Bazlul Karim Choudhury, M. Masudul Hassan, Ferdousi Rahman Mowsumi, Md. Shahdat Hossain and M. Shahabuddin Choudhury. Oyster mushroom ameliorates liver function during ramadan fast reflected by reducing the serum level of alanine aminotransferase and aspartate aminotransferase of male volunteers. International Journal of Nutrition and Metabolism, 3(10):123-127, 2011.

59.  Md. Bazlul Karim Choudhury1, A. J. Kakon, Taufiqur Rahman, Ferdousi Rahman Mowsumi, Md. Burhan Uddin2, M. Shahabuddin Kabir Choudhuri3 and Md. Shahdat Hossain. Oyster Mushroom (Pleurotus ostreatus) Improves Glycemic Status of Normotensive Diabetic Male Volunteers of Bangladesh. Bangladesh J. Mushroom, 5(2): 1-6, 2011 (December).

60.  Sina Ibne Noor, Nuruzzaman Masum, Zinia Nowshin, Shahdat Hossain, Shahidul Alam Khan, Tofail Ahmed, Ishtiaq Mahmud. Effect of thyroid status on lipid profile and its association with components of metabolic syndrome. Dhaka University Journal of Biological Science, 19(2): 159-164, 2011.

61.  Effect of Oyster Mushroom (Pleurotus ostreatus) on Renal Function of Hypertensive Diabetic Male Volunteers. Md. Bazlul Karim Choudhury, Nirod Chandra Sarker, Mahbuba Moonmoon, Tahera Binte Mujib, Mst. Masuda Begum, Md. Shahdat Hossain and M. Shahabuddin Kabir Choudhuri. Bangladesh J. Mushroom, 5(2): 53-58, 2011 (December).

62.  Bhuiyan ZA., Rokeya B., Masum N., Hossain S, Mahmud I, Antidiabetic effect of Syzygium cumini (L) seed on type II diabetic rats.  Dhaka University Journal of Biological Science, 19: 157-164, 2010.

63.  Md. Bazlul Karim Choudhury1, Ferdousi Rahman Mowsumi, Tahera Binte Mujib, Saleh Ahmed, Nirod Chandra Sarker, Md. Shahdat Hossain and M. Shahabuddin Kabir Choudhuri. Differential Effect of Pleurotus ostreatus on Hepatocellular Markers Alanine Aminotransferase and Aspartate Aminotransferase in Adult Male vs Female during Ramadan Fast. Bangladesh Journal of Mushroom, 4(1): 1-6, 2010 (June).

64.  Md. Bazlul Karim Choudhury1, Ferdousi Rahman Mowsumi, A. J. Kakon, Md. Shahdat Hossain and M. Shahabuddin Kabir Choudhuri. Oyster Mushroom Ameliorates Lipid Profile of Bangladeshi Women during Ramadan Fast. Bangladesh Journal of Mushroom, 4(2):1-8, 2010.

65.  Borhan Uddin, Taslima Nahar, Mafroz Ahmed Basunia, Tareq Hossan, M S K Choudhury, Shahdat Hossain. Ameliorative effects of Paederia foetida Linn. (Rubiaceae) extract on hepatotoxin-induced liver damage. Bangladesh Journal of Life Sciences, 22(2):57-63, 2010.

66.  Shahdat Hossain, Michio Hashimoto, Masanori Katakura, Koji Miwa, Toshio Shimada, Osamu Shido. Mechanism of docosahexaenoic acid-induced inhibition of in vitro A1-42 fibrillation and A1-42-induced toxicity. Journal of Neurochemistry, 111: 568-579, 2009.

67.  Michio Hashimoto, Hossain Md Shahdat, Masanori Katakura, Yoko Tanabe, Shuji Gamoh, Koji Miwa, Toshio Shimada, Osamu Shido. Effects of docosahexaenoic acid on in vitro amyloid beta peptide25-35 fibrillation. Biochemica Biophysica Acta, 1791: 289-296, 2009.

68.  Hashimoto M, Hossain S, Tanabe Y, Kawashima A, Harada T, Yano T, Mizuguchi K, Shido O. The protective effect of dietary eicosapentaenoic acid against impairment of spatial cognition learning ability in rats infused with amyloid beta1-40. Journal of Nutritional Biochemistry, 20:965-973, 2009.

69.  Masanori Katakura, Michio Hashimoto, Shahdat Hossain, Gamoh Shuji et al. Docosahexaenoic acid promotes neuronal differentiation by regulating basic helix-loop helix transcription factors and cell cycle in neural stem cells. Neuroscience, 19: 160, 651-880, 2009.

70.  Ishtiaq Mahmud, Sudip Debnath, Nuruzzaman Masum, Shamima Keka Islam, Shahdat Hossain. Serum Zinc Level Is Inversely Related with Hyperglycemia in Type 2 Diabetes Mellitus. Bangladesh Journal of Medical Science, 15:121-124, 2009.

71.  Md. Asaduzzaman Khan, Liakot A. Khan1, Md. Shahdat Hossain, Mousumi Tania and Md. Nazim Uddin. Investigation on the Nutritional Composition of Common Edible and Medicinal Mushrooms Cultivated in Bangladesh. Bangladesh Journal of Mushroom, 3(1): 21-28, 2009.

72.  N. Alam,  S. Hossain, M.I. Khalil, M.K. Alam, M.A. Khan. Upgrading of Animal Feed by Solid State Fermentation by Pleurotus sajor-caju. European Journal of Applied Sciences, 1(4): 53-58.

73.  Md. Bazlul Karim Choudhury, Ferdousi Rahman Mowsumi, Tahera Binte Mujib, Nirod Chandra Sarker, Md. Shahdat Hossain amd M. Shahbuddin Kabir Choudhuri. Effect of Oyster Mushroom (Pleurotus ostreatus) on hepatocellular markers Alanine Aminotransferase and Aspartate Aminotransferase of adult human during ramadan. Bangladesh Journal of Mushroom, 3(2):7-11, 2009.

74.  Md. Shahdat Hossain, Mohammad Azizur Rahman, Tofael Kabir Sarker and Hussain Md. Shahjalal. Formaldehyde content in the rui fish (labeo rohita) in bangladesh and effect of formaldehyde on lipid peroxidation in rat liver and intestinal tissues. Journal of Medical Sciences, 8: 405-409, 2008.

75.  Michio Hashimoto, Hossain Md Shahdat, Shinji Yamashita, Masanori Katakura, Yoko Tanabe, Hironori Fujiwara, Shuji Gamoh, Teruo Miyazawa, Hiroyuki Arai, Toshio Shimada, Osamu Shido. Docosahexaenoic acid disrupts in vitro amyloid beta (1-40) fibrillation and concomitantly inhibits amyloid levels in cerebral cortex of Alzheimer's disease model rats. Journal of Neurochemistry, 107(6):1634-46, 2008.

76.  Md. Mahabub-Uz-Zaman, Satya Ranjan Sarker, Md. Shahdat Hossain. The effects of industrial effluent discharge on lipid peroxide levels of punti fish (puntius sophore) tissue in comparison with those of freshwater fish. Journal of Food Lipids, 15(2):198 – 208, 2008.

77.  Michio Hashimoto, Shuji Gamoh, Masanori Katakura, Hossain Shahdat.  The role of  w-3 polyunsaturated fatty acids in Alzheimer's disease. The lipid (Japan), 19:409-416, 2008.

78.  Ishtiaq Mahmud, M. Anwar Hossain, M Sohrab Alam, Hussain M Shahajala, M. Shahdat Hossain. Synthesis and accumulation of polyamines in the liver of rats after treatment with carbon tetrachloride. Bangladesh Journal of Medical Science, 14:108-111, 2008.

79.  Shahdat Hossain, Azizur Rahman, Yearul Kabir, Ali Ahmed Shams, Fahmida Afros, Michio Hashimoto. Effects of shrimp (Macrobracium rosenbergii)-derived chitosan on plasma lipid profile and liver lipid peroxide levels in normo- and hypercholesterolaemic rats. Clinical and Experimental Pharmacology and Physiology, 34: 170-176, 2007.

80.  Shahdat Hossain, Hossain Uddin Shekhar, Mohammad Nazmul Hasan Khan, Fowzia Akter Selina, Fakhruddin Ali Ahmed, Yearul Kabir, Ishtiaq mahmud. Contents of Docosahexaenoic acid in the fresh water plankton of Bangladesh and its clinical importance. Bangladesh Journal of Medical Science, 13: 54-59, 2007.

81.  Md. Shahdat Hossain, Md. Ashraful Hasan, K. M. Golam Maola, Subrata Banik and Hussain Md. Shahjalal. Relationship between depression and blood pressure in young, middle-aged and elderly: a population based study in Bangladesh. Bangladesh Journal of Medical Science, 13:130-133, 2007.

82.  Borhan Uddin, Taslima Nahar, M. Ibrahim Khalil and Shahdat Hossain. In vitro antibacterial activity of the ethanol extract of Paederia foetida Linn. (Rubiaceae) leaves, Bangladesh Journal of Life Sciences, 2007. 19(2): 141-143.

83.  Md. Shahdat Hossain, Nuhu Alam, S.M. Ruhul Amin, M.A. Basunia, Azizur Rahman. Essential fatty acid contents of Pleurotus ostreatus, Ganoderma lucidum and Agaricus bisporus. Bangladesh Journal of Mushroom, 1:1-7. 2007 (June).

84.  Nuhu Alam, Md. Shahdat Hossain, Abul Khair, S.M. Ruhul Amin and Asaduzzaman Khan. Bangladesh. Comparative Effects of Oyster Mushrooms on Plasma Lipid Profile of Hypercholesterolaemic Rats. Bangladesh Journal of Mushroom, 1(1): 15-22, 2007 (June).

85.  Nuhu Alam, Asaduzzaman Khan, Md. Shahdat Hossain, S.M. Ruhul Amin and Liakot A. Khan Nutritional Analysis of Dietary Mushroom- Pleurotus florida Eger and Pleurotus sajor-caju (Fr.) Singer. Bangladesh Journal of Mushroom, 1(2): 1-7, 2007 (December).

86.  Azizur Rahman, Taslima Nahar, Alok K Paul, Tabassum Sirajam Munira, Shahdat Hossain and M. S. K. Choudhuri. Effects of chronic administration of Asokarista on the blood biochemical parameters of male rats. Bangladesh Journal of Biological Sciences, 19: 83-89, 2007.

87.  Hossain Uddin Shekhar, Yearul Kabir, Mosharaf Hossain, Mesbah Uddin, Kaniz-Khatun-E-Jannat, Shahdat Hossain and Hussain Shahjalal. Blood transfusion-mediated viral infections in thalassemic children in Bangladesh. Journal of Medical Sciences (Pakistan), 7: 131-135, 2007.

88.  Michio Hashimoto, Shuji Gamoh, Shahdat Hossain, Hideki Okunishi, Keiko Shimoura, Yukihiko Yasui, Akiro Ando, Sumio Masumura. Age‐related changes in aortic sensitivity to noradrenaline and acetylcholine in rats. Clinical and Experimental Pharmacology and Physiology, 25(9):676 – 681, 2007.

89.  Ahmed G, Hossain MS, Kabir Y, Jahan SS.Effects of Hilsa Ilisha fish oil, soybean and palm oil on the serum and liver lipids of experimentally-induced hypercholesterolemic rats. Pakistan Journal of Medical Research, 45: 53-58, 2006.

90.  Michio Hashimoto, Shahdat Hossain, Osamu Shido. Docosahexaenoic acid but not eicosapentaenoic acid withstands dietary cholesterol-induced decreases in platelet membrane fluidity. Molecular and Cellular Biochemistry, 293:1-8, 2006.

91.  Michio Hashimoto, Shahdat Hossain, Toshio Shimada, Osamu Shido.. Docosahexaenoic acid-induced protective effect against impaired learning in amyloid beta-infused rats is associated with increased synaptosomal membrane fluidity. Clinical and Experimental Pharmacology and Physiology, 33: 934-939, 2006.

92.  Michio Hashimoto, Hossain Shahdat, Haque Abdul, Osamu Shid. Docosahexaenoic acid-induced amelioration on impairment of memory learning in amyloid -infused rats relates to the decreases of amyloid  and cholesterol levels in detergent-insoluble membrane fractions. Biochimica Biophysica Acta: Molecular and Cell Biology of Lipids, 1738: 91–98, 2005.

93.  Michio Hashimoto, Hossain Shahdat, Yoko Tanabe, Osamu Shido.  Effects of aging on the relation of adenyl purine release with plasma membrane fluidity of arterial endothelial cells. Prostaglandins Leukot Essent Fatty Acids, 73: 475-83, 2005.

94.   Ishtiaq Mahmud, Md. Shahdat Hossain, Hossain Uddin Shekhar, Muhammad Shafiqur Rahman and Hussain Md. Shahjalal. Relevance of serum polyamine levels in the diagnosis of human prostate and lung cancers. Bangladesh Journal Life Sciences, 17: 7-14, 2005.

95.  Ishtiaq Mahmud, Md. Abdul Haque, G. M.A. Hannan, Md. Shahdat Hossain, Yearul Kabir, Hossain Uddin Shekhar, Liaquat Ali.  The differential effects of soybean and Hilsa ilsa fish oil on the lipid profile and glycemic status of streptozotocin-treated type 2 diabetic rats. Dhaka University Journal of Biological Sciences, 14: 33-42, 2005.

96.  Hossain Shahdat, Michio Hashimoto, Toshio Shimada and Osamu Shido. Synaptic plasma membrane-bound acetylcholinesterase activity is not affected by docosahexaenoic acid-induced decrease in membrane order: Life Sciences, 74: 3009-3024, 2004.

97.  Md. Shahdat Hossain, Ishtiaq Mahmud, Hossain Uddin Shekhar, Yarul Kabir, and Michio Hashimoto. The fallacy of cholesterol-free vegetable oil and the effects of fatty acid composition of vegetable versus fish oils on health and diseases. Bangladesh Journal of Nutrition, 16: 129-147, 2004.

98.     Yoko Tanabe, Michio Hashimoto, Kozo Sugioka, Megumi Maruyama, Yoshimi Fujii, Rika Hagiwara, Toshiko Hara, Shahdat Hossain and Osamu Shido. Improvement of spatial cognition with dietary docosahexaenoic acid is associated with an increase in Fos expression in rat CA1 hippocampus. Clinical and Experimental Pharmacology and Physiology, 31: 700-703, 2004.

99.     Ishtiaq Maimed, Anwar Hossain, Shahdat Hossain, Abdul Hannan, Liaquat Ali and Michio Hashimoto. Effects of Hilsa ilisa fish oil on the atherogenic lipid profile and glycaemic status of streptozotocin-treated type 1 diabetic rats. Clinical and Experimental Pharmacology and Physiology, 31: 76-81, 2004.

100. Farzana Binte Rahman, Emran Kabir Chowdhury, Shahdat Hossain, Abdul Hannan, Sharmin Rumi Alim, Hossain Uddin Shekhar, Liaqot Ali, Md. Atiqur Rahman and Ishtiaq Mahmud. .Effect of Pangas (Pangusius pangasius) fish oil on atherogenic factors in diabetic rats. Bangladesh Journal Life Science, 16: 61-69, 2004.

101. Shahdat Hossain, Michio Hashimoto, Emran Kabir Chowdhury, Nuhu Alam, Shahjalal Hussain, Moynul Hasan, Shahabuddin Kabir Chowdhury and Ishtiaq Mahmud. Dietary mushroom (Pleurotus ostreatus) ameliorates atherogenic lipid in hypercholesterolaemic rats. Clinical and Experimental Pharmacology and Physiology, 30: 470-475, 2003.

102. Michio Hashimoto, Kuninori Shiwaku, Akikko Nogi, Yoshimi Fujii, Erdembileg Anuurad, Enkhmaa Byamba, Keiko Kitajima, Hossain Md. Shahdat, Yosuke Yamane, Tsendsuren, Osamu Shido. Effect of dietary intake on body composition, blood pressure and serum lipid profiles—comparison between Mongolian and Japanese workers. Japanese Journal of Food Chemistry, 10: 46-50, 2003.

103. Shahdat Hossain, Ishtiaq Mahmud and Michio Hashimoto. Age-related alterations in platelet aggregation correlates with platelet volume parameters and lipid peroxide levels. Bangladesh Journal of Medical Science, 9: 69-74, 2003.

104. Ishtiaq Mahmud, Hussain Md. Shahjalal, Abdul Hannan, Sohrab Alam, Md. Shahdat Hossain, Hossain Uddin Shekhar, Liaquat Ali, Nilufar Nahar and Rafiqur Rahman. Growth inhibitory activity of Urginea indica plant extract associated with decreased polyamine levels in the partially hepatectomized rats. Bangladesh Journal of Life Science, 15:7-15, 2003.

105. Michio Hashimoto, Shahdat Hossain, Toshio Shimada, Kozo Sugioka, Hiroshi Yamasaki, Yoshimi Fujii, Yutaka Ishibashi, Jun-Ichiro Oka and Osamu Shido. Docosahexaenoic acid provides protection from impairment of learning ability in Alzheimer`s disease model rats. Journal of Neurochemistry, 81: 1084-1091, 2002.

106. Michio Hashimoto, Md. Shahdat Hossain, Toshio Shimada, Hiroshi Yamasaki, Yoshimi Fujii, Yutaka Ishibashi and Osamu Shido. Relationship between age-related increases in rat liver lipid peroxidation and bile canalicular plasma membrane fluidity. Experimental Gerontology, 37: 89-97, 2001.

107. Michio Hashimoto, M. Shahdat Hossain, Toshio Shimada, Hiroshi Yamasaki, Fuji Yoshimi and Osamu Shido. Effects of docosahexaenoic acid on annular lipid fluidity of the rat bile canalicular plasma membrane. Journal of Lipid Research, 42: 1160-1168, 2001.

108. Shuji Gamoh, Michio Hashimoto, Shahdat Hossain and Sumio Masumura. Chronic administration of docosahexaenoic acid improves the performance of radial arm maze task in aged rats. Clinical and Experimental Pharmacology and Physiology, 28: 266-270, 2001.

109. Michio Hashimoto, Shuji Gamoh, Shahdat Hossain and Sumio Masumura. The prophylactic effect of docosahexaenoic acid on the senile dementia. Folia Pharmacology of Japan, 118 (suppl. 1): 106-108, 2001.

110. Michio Hashimoto, Kazumasa Shinozuka, Tesuya Sasaki, Naoko Tanaka, Shahdat Hossain, Yoko Kubota, Katsuhiro Tamura, Osamu Shido and M. Kunitomo. Nicorandil-induced ATP release in endothelial cells of rat caudal artery is associated with increase in intracellular Ca2+. European Journal of Pharmacology, 416: 179-183, 2001.

111. Michio Hashimoto, Kazumasa Shinozuka, Shuji Gamoh, Yoko Tanabe, Md. Shahdat Hossain, Young Mi Kwon, Noriaki Hata, Yoshihisa Misawa, Masaru Kunitomo and Sumio Masumura. The hypotensive effect of docosahexaenoic acid is associated with the enhanced release of ATP from the caudal artery of aged rats. Journal of Nutrition, 129: 70-76, 1999.

112. Michio Hashimoto, Kazumasa Shinozuka, Yoko Tanabe, Shuji Gamoh, Toshiko Hara, M.S. Hossain, Young Mi Kown, Masaru Kunitomo and Sumio Masumura. Hypotension induced by exercise is associated with enhanced release of adenyl purines from aged rat artery. American Journal of Physiology, 276: H970-975, 1999.

113. Md. Shahdat Hossain, Michio Hashimoto, Shuji Gamoh and Sumio Masumura. Antioxidative effects of docosahexaenoic acid in the cerebrum versus cerebellum and brain stem of aged hypercholesterolemic rats. Journal of Neurochemistry, 72: 1133-1138, 1999.

114. Michio Hashimoto, Shahdat Hossain and Sumio Masumura. Effect of aging on plasma membrane fluidity of rat endothelial cells. Experimental Gerontology, 34: 687- 698, 1999.

115. Md. Shahdat Hossain, Michio Hashimoto, Shuji Gamoh and Sumio Masumura. Association of age-related decrease in platelet membrane fluidity with platelet lipid peroxide. Life Sciences, 64:135-143, 1999.

116. Md. Shahdat Hossain, Michio Hashimoto and Sumio Masumura. Age-related changes in platelet microviscosity and aggregation in rats. Clinical and Experimental Pharmacology and Physiology, 26: 426-432, 1999.

117.   Michio Hashimoto, Md. Shahdat Hossain, Hiroshi Yamsaki, Kazunaga Yazawa and Sumio Masumura. Effects of eicosapentaenoic acid and docosahexaenoic acid on plasma membrane fluidity of aortic endothelial cells. Lipids, 34: 1297-1304, 1999.

118.   Shuji Gamoh, Michio Hashimoto, Kozo Sugioka, M. Shahdat Hossain, Noriaki Hata, Yoshihisa Misawa and Sumio Masumura. Chronic administration of docosahexaenoic acid improves reference memory-related ability in young rats. Neuroscience, 93: 237-241, 1999.

119.     Md. Shahdat Hossain, Michio Hashimoto and Sumio Masumura. Influence of docosahexaenoic acid on cerebral lipid peroxide level in aged rats with and without hypercholesterolemia. Neuroscience Letters, 244: 157-160, 1998.

120.    Michio Hashimoto, Kazumasa Shinozuka, Hossain M. Shahdat, Young Mi Kwon, Yoko Tanabe, Masaru Kunitomo and Sumio Masumura. Antihypertensive effects of all-cis-5,8,11,14,17-icosapentaenoate of aged rats is associated with an increase in the release of ATP from caudal artery. Journal of Vascular Research, 35: 55-62, 1998.

121.    Michio Hashimoto, Kazumasa Shinozuka, Yoko Tanabe, Hossain Md. Shahdat, Shuji Gamoh, Young Mi Kwon, Yasuakira Tanaka, Masaru Kunitomo and Sumio Masumura. Long-term supplementation with a high cholesterol diet decreases the release of ATP from the caudal artery in aged rats. Life Sciences, 63:1879-1885, 1998.

122.    Michio Hashimoto, Shuji Gamoh, Shahdat Hossain, Hideki Okunishi, Keiko Shimoura, Yukihiko Yasui, Akiro Ando and Sumio Masumura. Age-related changes in aortic sensitivity to noradranaline and acetylcholine in rats. Clinical and Experimental Pharmacology and Physiolog, 25: 676-681, 1998.

123.    Mohammed Shah Alam, Kwansong Ku, Masanobu Yamauchi, Michio Hashimoto, Seishi Nosaka, Mohammed Shahdat Hossain, Sumio Masumura, Kengo Nakayama and Katsuhiro Tamura. Protective effects of nicaraven, a new hydroxyl radical scavenger, on the endothelial dysfunction after exposure of pig coronary artery to hydroxyl radicals. Molecular and Cellular Biochemistry, 178: 237-243, 1998.

124.    Salamatullah Quazi, Shahdat Hossain, Ishtiaq Mahmud and S.A.M. Khairul Bashar. Dose effects of Pangas (Pangsius pangasius) fish oil and soybean oil on serum and liver lipids in experimental hypercholesterolemic rats. Dhaka University Journal Biological Sciences, 2: 69-76, 1993.

 

Abstracts published in the proceedings and/or symposiums)

125.    J. Hussain, M. Sarkar, S. Bhowmick, S. Hossain, Hot Water Extract of Moringa oleifera Leaves Protect Erythrocytes from Hemolysis and Major Organs from Oxidative Stress in vitro. National Conference on Biochemistry and Molecular Biology for Life Sciences, University of Dhaka, Dhaka, Bangladesh, Dec 2016.

126.    M. Sarkar, J. Hussain, S. Bhowmick, M. Hasan, S. Hossain. Acute Fear Stress Makes the Erythrocytes More Vulnerable to Oxidative Insults: a Study in Post-traumatic Stress Disorder Model (PTSD) Rats. National Conference on Biochemistry and Molecular Biology for Life Sciences, University of Dhaka, Dhaka, Bangladesh, Dec 2016.

127.    M. Hossain, S. Bhowmick, B. K. Choudhury, S. Hossain. Effects of Ganoderma lucidum on Oral Squamous Cell Carcinoma (OSCC) Patients: Evaluation of a Putative Palliative for Oral Cancer Patients at Post-Operative Stages, National Conference on Biochemistry and Molecular Biology for Life Sciences. University of Dhaka, Dhaka, Bangladesh, Dec 2016.

128.    S. Bhowmick, S. Jahan, L. S. Hossain. Maternal lead exposure decreases brain development and cognition-related proteins in the offspring. Conference on Contemporary Biomedical Research in Bangladesh, Rajshahi, Dec 2015.

129.    M. Sarkar, S.Bhowmick, M. Hassan, S. Hossain. in vitro Assesments of the Antioxidative and Antihemolytic Effects of Paddy Sprout Extract. International Conference on Biological Sciences: Food, Health and Environmental Perspectives, Rajshahi, Bangladesh. Aug 2015.

130.    S. Bhowmick, M. Hassan, M. Sarkar, S. Hossain. Antitumor activity of Curcuma longa extract. International Conference on Biological Sciences: Food, Health and Environmental Perspectives. Rajshahi, Bangladesh. Aug 2015.

131.    M. Hassan, S. Bhowmick, M. Sarkar, S.  Hossain. Anti-hypercholesterolemic effect of Auricularia polytricha (Ear mashroom). International Conference on Biological Sciences: Food, Health and Environmental Perspectives. Rajshahi, Bangladesh. Aug 2015.

132.    S. Bhowmick, M. Haque, M.J. Islam, A.Rahaman, S. Hossain. Chronic administration of Curcuma longa extract improves spatial memory-related learning ability in aged and Alzheimer’s disease Model rats.  National Conference on Biochemistry, Industry and Sustainable Economy, Rajshahi, Bangladesh. Aug 2015.

133.    Shahdat Hossain, Michio Hashimoto, Masanori Katakura, Osamu Shido . Asiaticoside and madecassoside, two major glycosides of Centella asiatica inhibit the in vitro amyloid beta peptide A1-42 fibrillation ─  assessed by FCS, capable of detecting single molecular movement and interaction. In: Mechanisms, clinical strategies, and promising treatments of neurodeenerative diseases: The 11th International Conference on Alzheimer’s & Parkinson’s Diseases, Florence, Italy, March 6-10, P245, 2013.

134.    Michio Hashimoto, Shahdat Hossain,, Masanori Katakura, Osamu Shido. Docosahexaenoic acid-induced decrease in conditioned freezing response is associated with increased expression of GRP- and TrKB receptors in the hippocampus. In: Mechanisms, clinical strategies, and promising treatments of neurodegenerative diseases: The 11th International Conference on Alzheimer’s & Parkinson’s Diseases, Florence, Italy, March 6-10, P 248, 2013

135.    M Hashimoto, H Shahdat, M Katakura, Y Tanabe, H Arai, O Shido. The binding of beta-amyloid 42 to lipid rafts containing detergent-resistant membranes of RBC ghost is enhanced by dietary docosahexaenoic acid in rats: An implication of erythrocyte functions to Alzheimer's disease . Alzheimer's and Dementia 07/2013; 9(4):189.

136.    Michio Hashimoto, Shahdat Hossain,, Masanori Katakura, Osamu Shido, Protective effects of docosahexaenoic acid on cognitive decline with aging and dementia: From animal and human interventional studies. In: The 17th Takeda Science Foundation Symposium on Bioscience: Therapeutic Approach for Neurogenerative Diseases: Focusing on Alzheimer’s and Parkinson Disease, P70, Dec, 6-7, 2012.

137.    Masanori Katakura, Michio Hashimoto, Shahdat Hossain, Osamu Shido, Omega-3 polyunsaturated fatty acids enhance neuronal differentiation in cultured rat neural stem cells, In: The 17th Takeda Science Foundation Symposium on Bioscience: Therapeutic Approach for Neurogenerative Diseases: Focusing on Alzheimer’s and Parkinson Disease, P67, Dec, 6-7, 2012

138.    Shahdat Hossain, Michio Hashimoto, Masanori Katakura, Osamu Shido, Docosahexaenoic acid inhibits amyloid beta peptide (Ab1-42 fibrillogenesis by inhibiting the formation of di-, tri-,-tetra – and oligomer amyloid intermediate soecies destined for matured fibers. In: The 17th Takeda Science Foundation Symposium on Bioscience: Therapeutic Approach for Neurogenerative Diseases: Focusing on Alzheimer’s and Parkinson Disease, P71, Dec, 6-7, 2012.

139.    Michio Hashimoto, Ryuichi Tozawa, Masahiro Katakura, Hossain Shahdat, Abdul Haque, Yoko Tanabe, Osamu Shido. Prescription omega-3 fatty acid-induced prevention of impairment of memory learning in amyloid-beta-infused rats associates with the decrease of amyloid-beta levels in detergent-insoluble membrane fractions  Alzheimers & Dementia - ALZHEIMERS DEMENT. 01/2011; 7(4).

140.    M Hashimoto, S Hossain, M Katakura. Preventive and ameliorative effects of n-3 polyunsaturated fatty acids on Alzheimer's disease  Intelligent Transportation Systems Journal 01/2010; 112:30.

141.    M Hashimoto, S Hossain, M Katakura. Preventive and ameliorative effects of n-3 polyunsaturated fatty acids on Alzheimer's disease. Journal of Pharmacological Sciences. 01/2010; 112:30.

142.    Shahdat Hossain, Shuji Gamoh, Masanori Katakura, Michio Hashimoto. The role of docosahexaenoic acid for the constitution, function and maintenance of central nervous system. Neuroscience, p. SY3A-G3, p. 75, 2008.

143.    Michio Hashimoto, Shahdat Hossain , Yoko Tanabe , et al., The protective effect of dietary eicosapentaenoic acid on the impairment of spatial cognition learning ability in Amyloid β peptide1-40-infused rats.  Alzheimer's and Dementia, Volume 4, Issue 4, Pages T250 - T250, 2008.

144.    Shahdat Hossain, Shuji Gamoh, Masanori Katakura and Michio Hashimoto. The role of docosahexaenoic acid for the constitution, function and maintenance of central nervous system. Neuroscience Research 61:2008, S1-S281, 2008.

145.    Michio Hashimoto. Shahdat Hossain, Shuji Gamoh, Masanori Katakura, Michio Dietary ecosapentaenoic acid protects against the impairment of learning ability in Alzheimer’s disease model rats. Neuroscience, P1 e01, p 148, 2008.

146.    Michio Hashimoto, Masanori Katakura, Yoko Tanabe, Shahdat Hossain, Shuji Gamoh, Teruo Miyazawa, Hiroyuki Arai, Osamu Shido. Protective and ameliorative effects of n-3 polyunsaturated fatty acid on dementia. Journal of Pharmaceutical Sciences 103 (Suppl. I) 20P, 2007.

147.    Shahdat Hossain, Michio Hashimoto, Toshio Shimada, Osamu Shido. Synaptic plasma membrane-bound acetylcholinesterase activity is not affected by docosahexaenoic acid –induced decrease in membrane order. (2007). J. Lipid Nutr. 16 (2): 198, 2007.

148.    Sheikh Ruhul Amin, Nuhu Alam, Asaduzzaman Khan, Shahdat Hossain. Comparative effects of oyster mushrooms on plasma lipid profile and liver and kidney functions-related parameters of hypercholesterolaemic rats. J. Lipid Nutr. 16 (2) : 199, 2007.

149.    Ishtiaq Mahmud, Shahdat Hossain, Abdul Hannan, Liakot Ali, Michio Hashimoto. Effects of Hilsa ilisa fish oil on the atherogenic lipid profile and glycaemic status of streptozotocin-treated type 1 diabetic rats.  J. Lipid Nutr. 16 (2) : 196, 2007.

150.    Nuhu Alam, Sheikh Md. Ruhul Amin, Shahdat Hossain, Shahjalal Hussain, Ishtiaq Mahmud. Pleurotus ostreatus mushroom ameliorates atherogenic lipid in hypercholesterolaemic rats. J. Lipid Nutr. 16 (2): 196, 2007.

151.    Michio Hashimoto, Shahdat Md. Hossain, Yoshimi Fujii, Naoko Tanaka, Masaru Kunitomo, Kazumasa Shinozuka, Osamu Shido. Effect of membrane fluidity on adrenoceptor stimulation-induced ATP release from vascular endothelial cells. The 4th International Symposium on Receptor Mechanisms, Signal Transduction and Drug Effects. Fukui, Japan, May 22-24, 2003.

152.    Hossain MS. Essential Fatty Acid Contents of Pleurotus ostreatus, Ganoderma lucidium and Agaricus bisporous. In: Project Reports of the Faculty of Biological Sciences, Jahangirnagar University, Savar, Dhaka-1342, Bangladesh. 2002.

153.    Hashimoto M, Hossain MS, Fujii Y, Tanabe Y, Adachi K, Edahiro K, Ishikawa S, Ito S, Nakajo M, Shibata N, Tanaka N, Shinozuka K and Shido O. Age-related decrease in the release of ATP from rat caudal artery may be resulted from decrease in plasma membrane fluidity of the vessel. 10th International Symposium on Vascular Neuroeffector Mechanisms. Granlibakken, Lake Tahoe, USA, July 12-15, 2002.

154.    Hashimoto M, Hossain MS, Fujii Y, Yamasaki H and Shido O. Effects of antioxidative defence of docosahexaenoic acid in the cerebral cortex and hippocampus of the Alzheimer’s disease model rats. Japanese Journal of Physiology (Supplement): 53S 206, 2002.

155.    Michio Hashimoto, M. Shahdat Hossain, Toshio Shimada, Hiroshi Yamazaki, Fuji Yoshimi and Osamu Shido. Effects of docosahexaenoic acid on annular lipid fluidity of the rat bile canalicular plasma membrane. Journal of Lipid Research 42: 1160-1168, 2001.

156.    Michio Hashimoto, Md. Shahdat Hossain, Hiroshi Yamazaki, Fuji Yoshimi, Jun-Ichiro Oka and Osamu Shido. Docosahexaenoic acid protects memory impairment in Alzheimer`s disease. The 5th international conference on progress in Alzheimer`s and Parkinson`s disease. Kyoto International Conference Hall, March 31- April 5, Kyoto, Japan, 2001.

157.    Md. Shahdat Hossain, Michio Hashimoto. Antioxidative effects of docosahexaenoic acid in the cerebrum versus cerebellum and brain stem of aged hypercholesterolemic rats. 4th Congress of the International Society for the Study of Fatty Acids and Lipids (ISSFAL), June 4-9, 2000, Tsukuba International Congress Center, Tsukuba, Japan. P-5-37, 2000.

158.    Michio Hashimoto, Md. Shahdat Hossain, Hiroshi Yamasaki, Keizo Umegaki, Yoshimi Fujii, Noriaki Hata, Yoshihisa Misawa, Toshio Shimada and Osamu Shido. Effects of dietary docosahexaenoic acid on the liver plasma membrane fluidity and membrane bound 5`-nucleotidase activity of aged rats. In: 4th Congress of the International Society for the Study of Fatty Acids and Lipids (ISSFAL), June 4-9, 2000, Tsukuba International Congress Center, Tsukuba, Japan. P-5-37, 2000.

159.    Md. Shahdat Hossain, Michio Hashimoto, Hiroshi Yamazaki, Yoshimi Fuji, Noriaki Hata, Yoshihisa Misawa and Osamu Shido. Relationship between annular-lipid fluidity and membrane -bound enzyme activity of rat bile canalicular plasma membrane. Journal of Lipid Nutrition 9: p -09, 122, 2000.

160.    Md. Shahdat Hossain, Suguru Kunitomo and Takatoshi Esahi. Chronic docosahexaenoic acid supplementation potentiates the negative inotropic effect of aged rats atrium. Japanese Journal of Pharmacology 82: Supplement I, P-316, 098 p, 2000.

161.    Hashimoto, N. Tanaka, K Shinozuka, M.S. Hossain, O. Shido, M. Kunitomo. Association of nicorandil-induced ATP release with an increase in intracellular calcium in endothelial cells of rat caudal artery. Journal of Submicroscopic Cytology and Pathology 32: A140, 2000.

162.    M Hashimoto, MS Hossain, H Yamazaki, S Ishikawa, K Yazawa and S Masumura. Effects of -3 polyunsaturated fatty acids on plasma membrane fluidity and lipid profiles of cultured endothelial cells. Japanese Journal of Lipid Nutrition 7: 138, 1998.

163.    M Hashimoto., Gamoh, S., Hossain, M.S., Hara, T., and Masumura, S. Effects of polyunsaturated fatty acids and noradrenaline on ATP release from tail arteries of hypercholesterolemic aged rat. Japanese Journal of Physiology 48 (suppl), S210, 1998.

164.    Gamoh S., Hashimoto M., Hossain M.S., Hara T., Masumura S.. Chronic administration of docosahexaenoic acid improves learning ability in the young and adult rats on radial-arm maze performance in young rats. The Japanese Journal of Physiology 48:187, 1998.

165.    Michio Hashimoto, Kazumasa Shinozuka, Shuji Gamoh, Yoko Tanabe, Md. Shahdat Hossain, Young Mi Kwon, Masaru Kunitomo and Sumio Masumura. Dietary effects of docosahexaenoic acid on the release of ATP from the caudal artery of aged rats. Japanese Journal of Physiology 76 (suppl, I), 181 P, 1998.

166.    M. Hashimoto, K. Shinozuka, Y. Tanabe, S. Gamoh, M.S. Hossain, Y.M. Kwon, M. Kunitomo and S. Masumura. Hypotensive effect of major components in fish oils, EPA and DHA, on aged rats is associated with an increase in therelease of ATP from the artery. Naunyn-Schmiedeberg`s Archives of Pharmacology 358: (Suppl 1), R 237, 1998.

167.    Gamoh S., Hashimoto M., Hossain M.S., Hara T. and Masumura S. (1995) Chronic administration of docosahexaenoic acid improves learning ability in the young and adult rats. on radial-arm maze performance in young rats. Japanese Journal of Physiology 48 (Suppl): S187, 1998.

168.    Hashimoto M., Shinozuka K, Yoko T., Gamoh S., Hossain M.S, Young M. K., Kunitomo M. and Masumura S. Antihypertensive effects of exercise of hypercholesterolemic aged rats is associated with an increase in the release of ATP from the caudal artery. Nagano Symposium on Sports Science for the Winter Olympic Games, P 105, 1997.

169.    Hashimoto M., Gamoh S., Hossain M.S., Hara T. and Masumura S. Effects of transmural pressure on the release of nitric oxide and prostacyclin from pig endocardial and vascular endothelial cells. Japanese Journal of Physiology 47(Suppl. 2): S79, 1997.

170.    Hashimoto M, Tanabe Y, Shinozuka K, Gamoh S., Hossain M.S., Kwon YM, Kunitomo M and Masumura S. Age-related change in vasorelaxation responses to nitric oxide and peroxynitrite of rat aorta. Japanese Journal of Pharmacology 73(Suppl. I): 37P, 1997.

171.    Gamoh S., Hashimoto M., Hossain M.S, Hara T. and Masumura S. The effect of docosahexaenoic acid (DHA) on radial-arm maze performance in young rats. Japanese Journal of Physiology 47: S181, 1997.

172.    Hossain M.S, Hashimoto M., and Gamoh S. Age-related change in biophysical properties of platelet membrane - A fluorescence life-time determined analysis. FASEB J. 11: 1259, 1997.

173.    Hossain M.S., Hashimoto M., Gamoh S. Hara T. and Masumura S. Age-related change in membrane fluidity in rat platelet. Japanese Journal of Physiology 46: S197, 1996.

174.    Hossain M.S., Hashimoto M., Hara T. and Masumura S. Age-related change in anti-platelet aggregation in feeding of a high fat diet and -3 fatty acid in rats. Japanese Journal of Pharmacology 67: P-165, 1995.

175.    Hashimoto M., Hossain M.S., Hara T. and Masumura S. A hypotensive effect of -3 fatty acids in the hypercholesterolemic aged-rats. Japanese Journal of Pharmacology 67: S13-5, 29P, 1995.

176.    Hashimoto M., Hossain M.S. Hara T. and Masumura S. Age-related changes in anti-platelet aggregation of a high fat diet and w-3 fatty acid in rats. Japanese Journal of Physiology 45: S259, 1995.

 

Book Chapters:

1.      Shahdat Hossain and Michio Hashimoto. Mechanism of Neurotoxicity of Amyloid-Beta Peptide and the Protective Effects of Docosahexaenoic Acid (Chapter 4). In:  Amyloids: Composition, Functions and Pathology. Editors: Irene P. Halcheck and Nancy R. Vernon. Pp: 83-102. Nova Science Publishers, Inc. 400 Oser Avenue, Suite 1600, Hauppauge, N.Y. 11788-3619, 2011. ISBN: 978-1-62100-538-4.

          

 

2.      Michio Hashimoto, Shahdat Hossain and Masanuri Katakura.   Docosahexaenoic acid and cognitive dysfunction.  Editors: Victor R. Preedy Ronald Ross Watson Colin R. Martin. Handbook of Behavior, Food and Nutrition, pp 1797-1813, (DOI 10.1007/978-0-387-92271-3_117, 2011. Print ISBN: 978-0-387-92270-6; Online ISBN: 978-0-387-92271-3, Publisher, Springer New York. Springer Science.

3.      Michio Hashimoto, Shahdat Hossain.  Effects of Dietary Docosahexaenoic Acid on Spatial Cognition of Normal and Alzheimer’s Disease Model Rats; pp. 265-284 (Chapter XI). . In: Omega-3 Fatty Acids Research. Editors: M. C. Teale  Nova Science Publishers, Inc. 400 Oser Avenue, Suite 1600, Hauppauge, NY 11788 (2006).  ISBN: 1-59454-620-7.

4.      Gamoh Shuji, Hossain Shahdat, Michio Hashimoto. Current Opinions regarding Fish Oils as Remedies in the Near Future, In ‘Fish Oils and Health.

5.      Editors: Eetu P. Heikkinen, NOVA Publishers, New York, USA, pp. 87-115, 2008. ISBN: 978-1-60456-428-0. Michio Hashimoto, Shahdat Hossain, Fatty acids- as membrane ingredients to signaling molecules. In Fatty Acids, IntechOpen, UK. (In press).

 

6.      Scientific indicators and summary of achievements from citation records

a.       Citation Records of my publications in Google Scholar database: https://scholar.google.com/citations?user=Sa4StfYAAAAJ&hl=en&oi=ao

b.      Citation Records of my publications in Research Gate database: https://www.researchgate.net/profile/Shahdat_Hossain

c.       Citation Records of my publications in orcid:  http://orcid.org/0000-0003-2970-2324

d.      ResearcherID: ID: http://www.researcherid.com/ProfileView.action?returnCode=ROUTER.Unauthorized&queryString=KG0UuZjN5WllT1umui5SVYKRlmr6OQtVT7keYis6dzY%253D&SrcApp=CR&Init=Yes

 

 


Academic Info

Institute: Department of Biochemistry, University of Dhaka,
Period: 1986

B.Sc. (Hons)

Institute: Department of Biochemistry, University of Dhaka
Period: 1987

M.Sc.

Institute: Department of First Physiology, Shimane Medical University, Izumo- 693, Shimane, Japan
Period: October 1993- March 31 1995

Research Studentship

Institute: Department of First Physiology, Shimane Medical University, Izumo- 693, Shimane, Japan
Period: June 1997- March 1998.

Teaching assistantship 

Institute: Department of First Physiology, Shimane Medical University, Izumo-693, Shimane, Japan
Period: June 1998- March 1999.

Research assistantship

Contact

Shahdat Hossain

Professor
Department of Biochemistry & Molecular Biology
Jahangirnagar University, Savar, Dhaka-1342, Bangladesh.
Cell Phone: +8801817544672
Email: shahdat@juniv.edu , shahdat@dhaka.net